I've been out of the modding scene for awile, busy with life etc and I recently decided to finally play Skyrim. After doing extensive reading, I was pretty excited by the idea of a mod manager that supported profiles - separate characters and mod sets. The amount of effort I once put into trying to have different saves by having multiple copies of the data or whole game folder on Fallout 3 with FOMM, BOSS, FO3Edit etc. Overall the VFS idea is pretty cool.
I'm very rusty but so far I've managed to successfully set up a few mods on SkyrimSE with MO2 and clean a few ESM's thru xEdit.
Without Wrye Bash or SKSE installed in the game directory, as a test, I was able to completely uninstall and reinstall SSE and picked back up from MO and the local save like the game had never been removed.
Also, Something I came across while starting to read up on Wrye Bash, was a way to use it from a separate directory from the game by editing bash.ini to point to the game (I haven't tested it)
My question then is aside from the SKSE and maybe WB, are there any other things that could cause problems while trying to pull that off? I know this might sound a little crazy but the possibility of having not just a mod archive but a functioning load order and save to just drop in and run with is hard to pass up.
Anyone else have any experience trying this?