quick update to say that the crashing is definitely been reduced greatly. Only had 2 crashes and neither of them while roaming the wasteland. The first one was when i spoke to Amata after opening the vault door, which didn't repeat after a reload, and the second was when entering megaton, again only once so far.
So far everything seems good except Lucas Simms has invisible arms that i can't seem to fix. I am using Roberts males and didn't get the optional Breezes clothing items, if that makes any difference, so if anyone has any ideas about that then i would be grateful. He is the only NPC that has this problem but some of the others occasionally and depending on my position when looking at them have these strange lines projecting from different parts on them, mainly the head, but im putting this down to load order and will keep playing around with it.
One more question i have is regarding the wasteland patch collection and letting some of them get merged into the bashed patch. I deactivated them becasue i assumed it would not be a good idea but is it actually safe to do so and are their any others in the guide that shouldn't be included?
Thanks again for any help.