I'm currently working on organizing my current notes for running Perkus Maximus on a large mod list. Read Skyrim Revisited - Legendary Edition + REGS + Perkus Maximus with some of my other favorite goodies sprinkled in. I'm using WB 306 Beta and am not seeing any issues (after sorting out a problem I was having with the perk tree names). It might take me a while since writing HTML with inline CSS is not one of my favorite things to do. I will be updating as I find things or more patches are made for the patcher and bugfixes are made. Oh. Also I use LOOT for sorting so I'll probably be including any necessary LOOT instructions though I doubt they're even needed.
Some notable things are I'm not using ASIS from SR:LE or any of the Gameplay Affecting Quests Mods from REGS.