So far, I've been able to run this guide up to Requiem version 2.0.2, with very minor adjustments.
Unfortunately, I wasn't able to use any version past that because many of the patches don't exists.
However, I am having a corrupted mesh warning on loading a new game. I know this hasn't been updated in a while, but I'm going to keep a log of sorts, anyway.
Up to now, the biggest 2 issues I've come across have been discrepancies in the load order and mods listed in the SMC which are no longer in existence.
As for the load order, a few files are no longer needed (Hearthfires patches) and a few are in the load order.txt file that are not in the guide, for example: LSFX-Audiosettings.esp and CLARALUX Merged.esp
As for SMC mods no longer available? I went to Chinese sites, Korean sites, and Russian sites as well as reddit. Some are just not there anymore, but that's more an issue with SMC as their absence is really not likely to be noticed in-game.