The other approach is to add some settings to your Skyrim.ini, assigning specific jobs to the different CPU cores. Following this guide assigns 2 cores to rendering, and 2 cores to AI and such.
The .ini additions (for 4 cores):
Now, you can't use both of these together, as doing one of these changes nullifies the other. Has anyone played around with these and can supply some insight on which approach seems to be working best for you? I will try out the .ini changes for starters myself, but actually comparing the two probably takes quite a lot of testing and thus if someone has already done so, sharing it would be great!