There seems to be a conflict between these mods. From an OBIS stickied comment:
6. There seems to be an issue with ASIS and OBIS. A certain perk added by ASIS causes the Crow bandits to freak out and CTD your game. If you can manually remove the perk "perkskillboost" from the crow bandits in the ASIS.esp post-patcher this will solve it. Otherwise either don't use ASIS or exclude ASIS from OBIS.